Production Supervisor

Our client, Legend Biotech, based in Zwijnaarde, is a global biotechnology company bringing the innovative CAR-T cell therapy to Ghent. With this, the Legend Biotech team makes a daily difference in the lives of many patients suffering from cancer and other life-threatening diseases.

They are currently in a phase of strong growth and are looking for motivated and dedicated team members

Jobomschrijving

As a Production Supervisor, you are responsible for the daily production process of personalized cell therapy, both for clinical and commercial purposes. You will lead various units within the CAR-T process and ensure safe and compliant production activities in accordance with cGMP requirements — all while coordinating and overseeing operations from your dedicated office workspace, maintaining a clear overview of the production floor and ensuring smooth cross-team collaboration.

Tasks:

• Lead and supervise operational units within the CAR-T production process, including component preparation, production support, CAR-T processing, filling & finishing, and cryopreservation.
• Act as the primary point of contact for production-related topics, ensuring smooth coordination with Manufacturing Operations, QC IPC, Quality, Facilities & Engineering, MS&T/Manufacturing Excellence, Training, Planning, and Supply Chain.
• Provide hands-on leadership on the shop floor, supporting teams in daily operations, troubleshooting, and decision-making in cGMP environments.
• Serve as a subject matter expert for Quality and Operations and play a key role during GMP inspections and external audits.
• Oversee production quality activities, including documentation management (procedures, work instructions, logs, transfer forms), batch record review and release, and compliance with cGMP standards.
• Coordinate quality system processes such as Change Controls, Deviations/Events, and CAPA.
• Guide and support team development through structured training and operational coaching.
• Drive operational excellence by leading process improvements focused on efficiency, cost reduction, and quality enhancement.

Who we are looking for:

• Bachelor’s or Master’s degree in Science, Bio-Engineering, Pharmacy, or a related field, or equivalent through experience.
• Minimum 3 years of experience in a production environment, preferably in biotech or biopharma.
• Strong experience in management, for example as a production lead, supervisor, or similar leadership role.
• Solid knowledge of cGMP regulations, cleanroom operations, and familiarity with Microsoft Office; experience with MES/EBR systems is a plus.
• Strong communication, organizational, and leadership skills with an empathetic and people-oriented management style.
• Positive, flexible, and capable of prioritizing, multitasking, and solving problems effectively, with a strong attention to detail.
• Fluent in English (additional languages are a plus).