Senior Director, Clinical Supply Chain
ESSENTIAL FUNCTIONS AND RESPONSIBILITIES Lead and develop clinical supply strategies across Phase 1–3 programs
Ensure uninterrupted supply of IMP across global, multi-region clinical trials
Lead the team in end-to-end clinical supply operations, including packaging, labeling, distribution, returns, reconciliation and destruction.
Provide strategy and support in global logistics, including import/export activities and depot strategy, ensuring compliance with country-specific labeling and regulatory requirements
Provide strategic leadership, cross-functional alignment, and operational oversight to ensure the successful execution of key activities across Clinical Operations, Quality, Regulatory, and CMC functions.
Contribute to and review clinical trial documentation, including clinical protocols, pharmacy manuals, batch records, drug labels, and shipping documentation. Provide oversight of IRT strategy, setup, and execution
Partner closely with CMC to align manufacturing schedules with clinical supply needs and scale-up activitiesOversee comparator sourcing and supply strategies as needed
Select, manage, and oversee external vendors (CDMOs, depots, packaging and logistics providers), including RFPs, SOWs, and performance management
Partner with QA on vendor qualification, audits, compliance activities, and the development and maintenance of supply chain-related SOPs and processes.
Ensure compliance with GcPs, and global regulatory requirements
Support inspection readiness and regulatory submissions related to clinical supply
Develop and manage clinical supply budgets, forecasts, and spend tracking
Provide regular updates to leadership on supply status, risks, and planning assumptions
Lead, mentor, and develop a small clinical supply team and build scalable processes to support company growth
EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES Bachelor’s degree in life sciences, supply chain, or related field
12+ years of experience in biotech/pharma supply chain with 4+ years of people management experience within a clinical supply chain organization.
Strong experience supporting Phase 2 and Phase 3 clinical trials
Proven experience supporting global clinical trials (including EU, APAC, Canada), including multi-region labeling and distribution requirements
Biologics experience required; oncology therapeutic area background strongly preferred
Demonstrated ability to operate in a hands-on role within a small to mid-size biotech environment
Strong expertise in clinical supply planning, forecasting, and inventory management
Experience managing external vendors, including CDMOs, depots, and logistics providers
Strong working knowledge of IRT systems and clinical supply infrastructure
Solid understanding of GcP guidelines, 21 CFR and Annex 13 requirements
Oncology experience strongly preferred
Experience supporting transition from early-stage to late-stage clinical development
Experience building or scaling clinical supply chain functions in an emerging biotech environment
Strong leadership and people management skills, with the ability to mentor and develop team members
Excellent cross-functional communication and stakeholder management skills
Ability to operate effectively in a fast-paced, evolving environment and navigate ambiguity
Strong problem-solving skills with a focus on practical execution
Job Type: Full-time
Benefits: · Annual bonus program · Incentive stock option plan · 401k plan with flat non-elective employer contribution · Comprehensive medical insurance with 90-100% employer-paid premiums · Dental and vision insurance · HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity) · Unlimited PTO · Generous holiday schedule; includes summer and winter company shutdown · Relocation assistance
Schedule: · Monday to Friday
Work authorization: · United States (Required)
Additional Compensation: · Annual targeted bonus %
Work Location: · On site (San Diego, CA)
EQUAL OPPORTUNITY EMPLOYER: Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.
Notice to Recruiters and Third-Party Agencies The Talent Acquisition team manages the recruitment and employment process for Janux. To protect the interests of all parties involved, Janux will only accept resumes from a recruiter once a fully-executed search agreement is in place. Agencies are hereby specifically directed not to contact Janux employees directly in an attempt to present candidates. Janux will consider any candidate for whom an Agency and/or Recruiter has submitted an unsolicited resume to have been referred, free of any charges or fees.