Technical Project Manager

Reporting to the Director, Technical Sales & Field Application Scientists, the Technical Project Manager will lead all aspects of project management, coordination, and implementation relative to the NGS Services Lab and related businesses of Twist Bioscience. This role owns execution from customer intake through delivery, driving scalability, process optimization, and cross-functional alignment across a technically complex, high-throughput service environment.

The role manages the full range of communications required to facilitate each project, including customers, sales & field application support, Twist customer service, Twist legal, and the Twist product management group — encompassing non-disclosure agreements, customer quotes, purchase orders, and statements of work.

What You'll Be Doing

Project Leadership for the NGS Service and Applications Lab

Intake, Scoping & Quoting

Serve as the technical and operational lead during project intake, translating customer needs into clearly scoped, executable NGS service programs (DNA, RNA, methylation, long-read)

Own project definition and intake, including:

Customer objectives — translate complex customer goals into optimized sequencing strategies and workflows

Scope, assumptions, and constraints

Workflow design and feasibility

Cost, timelines, dependencies, and deliverables

Success criteria aligned to customer outcomes

Partner with Sales and FAS to shape opportunities early , including:

Defining the right assay or sequencing approach

Identifying risks, tradeoffs, and alternative strategies

Setting realistic expectations with customers

Prepare and distribute quotes for NGS service projects; maintain an up-to-date, accessible database of issued quotations, NDAs, purchase orders, and statements of work

Post-Intake Execution

Own end-to-end project coordination following intake through final delivery, ensuring continuity between scoping, lab execution, and data delivery

Serve as the central coordination hub across all functions, including: Lab Operations, Bioinformatics, Customer-facing teams (Sales / FAS), and the Customers

Drive regular project syncs with the lab manager (daily/weekly) to track progress vs. timeline, identify risks, and ensure alignment across teams

Serve as the primary point of contact for project updates post-intake

Establish and maintain clear communication cadence, including: status updates, timeline changes, data delivery, and invoicing

Manage customer expectations proactively, especially around: turnaround time (TAT), data quality, and scope changes or technical challenges

Maintain real-time visibility of all active projects, including a transparent, accessible work-in-progress (WIP) list, in coordination with the lab team

Maintain accurate, timely records across all systems to enable up-to-date reporting on quotes issued, orders placed, orders in progress, and orders shipped

Follow applicable regulatory and quality requirements, including ISO 13485, for the service lab

Leadership & Continuous Improvement

Provide technical and project leadership to coordinators and cross-functional partners supporting the NGS service lab

Identify and drive process optimization and scalability improvements across the intake-to-delivery lifecycle

Support ad hoc strategic projects as required

What You'll Bring to the Team

PhD in Biology, Genetics, Genomics, Molecular Biology, Chemistry, or a related Life Science field

5+ years of relevant experience utilizing Next Generation Sequencing (NGS) technologies, including project or program management experience, with demonstrated experience in a customer-facing role

Expert understanding of NGS workflows (DNA, RNA, methylation, long-read) and the customer workflows the associated service offerings address

Proven track record managing complex, technical projects from intake through delivery that meet customer expectations

Proven ability to influence and lead cross-functional teams, and to work effectively with customers, internal operations, and sales teams

Outstanding leadership, teamwork, and communication skills

Hands-on, high-energy, positive attitude with a can-do approach that gets it done

Highly motivated and results-oriented, with the ability to work under pressure and a strong sense of urgency

Strong organizational skills and excellent problem-solving abilities

Must be able to work outside of regular work hours / a flexible schedule as needed

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations. San Francisco Bay Area Pay Range $164,000 — $203,000 USD