Bioprocess Operator (Fermentation)

About the Role

You’ll operate bioreactors at multiple scales, run downstream processes including chromatography, spray drying, filtration, and centrifugation, and conduct in-process testing to ensure production targets and product quality are consistently met.

What You Will Do

Upstream Operations

• Perform material handling including receiving, storage, and dispensing
• Operate fermentation processes including media preparations, sampling, adjustments, and charge out for plate, shake flask, 10L, and 100L bioreactors

Downstream Operations

• Operate batch/continuous centrifuge, decanter, high-pressure homogenisation, filtration, chromatography (including FPLC), spray drying, freeze drying, drum drying, solvent extraction, colloid mill, and filter press
• Perform CIP/SIP procedures as per SOP

In-Process Testing & Quality

• Conduct in-process testing including moisture analysis, pH, optical density, microscopy, dry/wet cell weight, SDS-PAGE, GC, and HPLC
• Complete all documentation (Batch Manufacturing Records, CIP, Maintenance, Calibration, and Cleaning Records) in accordance with GMP and GDP standards

Process Monitoring & Control

• Monitor and control processes via on-site panel and remotely through SCADA/Controls systems
• Monitor process trends and alarms; report plant utilities issues and liaise with vendors for recovery actions

Maintenance, Safety & Housekeeping

• Perform pre- and post-campaign activities, manual cleaning, and equipment inspection
• Perform basic maintenance of production equipment
• Conduct stock counts and generate shift reports; ensure proper shift handover communications
• Assist Process Engineers in troubleshooting deviations; report all actual, near-miss, and potential incidents
• Participate in 5S, lean manufacturing, and continuous improvement initiatives
• Assist in project commissioning and validation activities as required

What We Are Looking For

• Diploma or equivalent in Food Science/Technology, Biotechnology, Bioengineering, Chemical Engineering, or a related field
• Minimum 5 years of experience in food manufacturing or a related field; experience in fermentation is a strong advantage
• Knowledge of Good Manufacturing Practices (GMP) and Good Documentation Practices (GDP)
• Familiarity with food safety requirements; experience with ISO22000, FSSC22000, or BRC certification implementation is advantageous

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Ho Kah Yeow | R1879233

ScienTec Consulting Pte Ltd |11C5781