Senior Biostatistician / QSP Modeler (f/m/d)

Brunel GmbH NL MannheimNordrhein-WestfalenArbeitsagenturpublished 09/08/2026
Must-have:PythonAISeniorLead
Machine translation — original language: German.Show original

Your Tasks

Apply to us if you want to become part of a team that develops innovative solutions together and helps shape the future. Your expertise and passion are the key to our mutual success. Start your journey with us and take your career to the next level.

  • Construction, development, and further development of QSP platform models for various oncological mechanisms of action
  • Development and optimization of virtual patient cohorts to map clinical heterogeneity and support study designs
  • Application and further development of mathematical modeling approaches (differential equation models, statistical models, population models)
  • Integration of modern methods such as AI/ML to support literature evaluation, model construction, and optimization of virtual populations
  • Derivation of practice-relevant results to support dose finding, combination strategies, duration of therapy, and clinical study design
  • Close cooperation in an interdisciplinary team under the technical leadership of a Senior Pharmacometrician in the PMx Oncology environment
  • Translation of biological and medical questions into quantitative, mathematically describable models
  • Active participation in shaping the scientific and methodological structure of the new group

Your Qualifications

  • Completed studies (Master or Doctorate/PhD) in Mathematics, Biomathematics, Biostatistics, Engineering, Pharmacology, or comparable disciplines
  • Very good knowledge in the development and application of models based on differential equations
  • Experience in statistical modeling as well as in dealing with complex, data-driven biological systems
  • Very good programming skills in at least one of the following languages: R, Python, or MATLAB
  • Experience in drug development or in a pharmaceutical/biomedical research environment is an advantage
  • Demonstrable scientific experience and/or publications in the relevant field
  • Strong communication skills and enjoyment of interdisciplinary cooperation
  • Very good English skills are mandatory, German skills are an advantage

Your Benefits

We offer you a corporate culture characterized by the diversity of our employees as well as mutual appreciation - between employees and at all corporate levels. In addition to varied regular get-togethers with the local Brunel teams, this also includes regular feedback discussions about your challenges and perspectives with your Account Manager. With individual continuing education and training, you will be optimally supported and prepared for future projects. Permanent employment contracts, 30 days of vacation, working time accounts, and company, employer-funded pension schemes are a matter of course for us.

### This is what Brunel stands for

Working at Brunel means: attractive work tasks, extraordinary career perspectives, the security of an expanding engineering service provider, and the full diversity of engineering and IT. In the DACH-CZ region alone, we have 45 locations and development centers with accredited testing laboratories, and worldwide over 100 locations with more than 12,000 employees in over 40 countries. More than 45 years of international success and over 25 years in Germany. Stagnation means regression - with Brunel, you can make a difference!