Msca-dn PHD Position

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Working at Amsterdam UMC MSCA-DN PhD position in Gene Therapy for Leukodystrophies

Would you like to contribute to the development of gene therapies for rare neurological diseases? Join the POLARIS doctoral network and work on innovative gene therapy approaches for leukodystrophies in an international and interdisciplinary research environment.

MSCA-DN PhD position in Gene Therapy for Leukodystrophies Questions?

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€ 3.217 - € 4.077

36 hours per week

Locatie AMC

fixed-term

React until: 5 October 2026

The project

POLARIS doctoral network

POLARIS is a European Marie Skłodowska-Curie Doctoral Network focused on accelerating therapy development for leukodystrophies: rare genetic disorders affecting the brain's white matter. The network aims to strengthen the full translational pathway, from understanding disease mechanisms and developing disease models to preclinical therapy testing, clinical readiness and patient-informed treatment priorities.

To achieve this, POLARIS brings together expertise in leukodystrophy biology, advanced disease models, therapeutic innovation, biomarker development, clinical translation, patient engagement, and ethical, regulatory and health-economic aspects of therapy development. The network will train a cohort of doctoral candidates in an international and interdisciplinary environment, combining academic research, industry-based preclinical development, secondments, network-wide training and transferable-skills development.

PhD project

For this position, the recruiting organisation is Amsterdam UMC , in the Netherlands. You will be employed by Amsterdam UMC and embedded in the POLARIS consortium. Academic supervision and disease-specific expertise will be provided by Dr Niek van Til at the Amsterdam Leukodystrophy Center (ALC).

This doctoral project focuses on the ...