Scientist (m/f/d) (Protein Biomarker Assay Development and Validation)

About us

With employees from over 50 nations, CENTOGENE is a truly international company with offices is in Rostock, Berlin, Delhi, Boston, Valencia, Belgrade, and São Paulo.

We were born to help diagnostic patients with rare disease and today we evolved to help patients of all clinical specialties to make bold progress with guided solutions for physicians, their patients and pharma partners.

Your tasks

Your Responsibilities

Assay development and validation

Design, plan and execute development and validation studies for protein-based biomarker assays, e.g., ELISA and other immunoassays, proximity extension assays (PEA) and functional assays

Build robust, scalable and transferable assay workflows, and support assay transfer and the implementation of new technologies

Write high-quality validation documentation in line with internal and regulatory standards (GLP/GCLP)

Diagnostic quality and compliance

Develop and validate assays to quality standards suitable for diagnostic use, including potential in-house IVD assays in line with applicable EU regulations (e.g., IVDR)

Support clinical studies, from assay qualification to sample analysis and reporting

Handle patient samples and data responsibly and in compliance with EU data protection law (GDPR) and internal policies

Data analysis

Analyze and interpret experimental data with Excel, GraphPad Prism and R or Python, applying sound statistics to reach clear biological conclusions that guide project decisions

Use AI tools, including large language models (LLMs), responsibly for data analysis, literature research and documentation, in line with data protection and quality requirements

Where relevant, work with structured datasets and databases

Communication and collaboration

Work cross-functionally with R&D, Quality Assurance and external partners

Contribute to SOPs, reports, manuscripts and publications

Present your results internally, to partners and at scientific conferences

How you work

Your profile

Required

PhD in Biochemistry, Molecular Biology or a related field

Strong background in protein-focused biochemistry

Hands-on laboratory experience in developing and validating protein assays, e.g., immunoassays

Familiarity with working in GLP/GCLP environments

Confident data analysis with Excel and GraphPad Prism, and working experience with R and/or Python

Fluent English, written and spoken

German at A2 level or higher, and willingness to improve towards B1

A plus

Postdoctoral or industry experience

Experience with proximity extension assays and their readouts, qPCR and/or next-generation sequencing (NGS)

Knowledge of diagnostic regulations (e.g., IVDR) and data protection requirements (GDPR)

Experience with cellular models, ideally in a neurological context

Experience with, or strong interest in, the responsible use of LLMs and other AI tools in scientific work

Exposure to SQL or database environments

You plan, run and document your own studies in a structured and reliable way

You communicate results clearly, in writing and in presentations

You bring your own ideas, question existing approaches and want to help shape how the team works

Why us?

Translational research with direct relevance for patients with rare and neurodegenerative diseases

An international, multidisciplinary team and close collaboration with pharmaceutical partners

Room to take ownership of your projects, help build the team and keep learning

Support with German language courses

A 12-month contract with the possibility of transitioning to a permanent position